BDBM645407 US20240016810, Compound TABLE 16.20::US20240150358, Example 00186::US20240208964, Biochemistry 20

SMILES C(Oc1nc(nc2N(CCc12)c1ccccc1)N1CCOCC1)c1cccnc1

InChI Key InChIKey=WZVWOMFCMAGUMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 645407   

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKfyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo™ Kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 55nMAssay Description:The biochemical PIKfyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo™ Kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 55nMAssay Description:The biochemical PIKfyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo™ Kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 2.69E+3nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details