BDBM646492 US11911372, Example 3::US20240277683, Example 3

SMILES COc1ccccc1-c1cc(NS(=O)(=O)c2ccccc2)no1

InChI Key InChIKey=YGYSRFLRKNPAHH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 646492   

LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 2.14E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 2.14E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 3.26E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 3.26E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 2.05E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 2.05E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 4.01E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT8(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 646492BDBM646492(US11911372, Example 3 | US20240277683, Example 3)
Affinity DataIC50: 4.01E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent