BDBM647661 (5S)-2-(bicyclo[2.2.1]heptan-1-yl)-5- phenyl-2,5,6,7-tetrahydro-3H- pyrrolo[2,1-c][1,2,4]triazol-3-one::US20240025912, Compound 1-1

SMILES O=c1n2[C@@H](CCc2nn1C12CCC(CC1)C2)c1ccccc1

InChI Key InChIKey=CMIIQBBXRLIHDQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647661   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647661(US20240025912, Compound 1-1 | (5S)-2-(bicyclo[2.2....)
Affinity DataEC50:  21.6nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent