BDBM647696 (R)-2-(3-fluorobicyclo[1.1.1]pentan-1- yl)-5-phenyl-2,5,6,8-tetrahydro-3H- [1,2,4]triazolo[3,4-c][1,4]oxazin-3-one::US20240025912, Compound 1-78

SMILES FC12CC(C1)(C2)n1nc2COC[C@@H](c3ccccc3)n2c1=O

InChI Key InChIKey=CWUFHAYUSYIQDZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647696   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM647696(US20240025912, Compound 1-78 | (R)-2-(3-fluorobicy...)
Affinity DataEC50:  93.9nMAssay Description:In this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution; top compound concentration of 100000 nM) tit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent