BDBM648214 US20240025922, Example 185

SMILES Cc1c2NCCOc2ncc1N1CCc2cnc(Nc3ccc(Cn4nccn4)cc3)nc2C1

InChI Key InChIKey=UQDMPNLTWHNBIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 648214   

LigandPNGBDBM648214(US20240025922, Example 185)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent

LigandPNGBDBM648214(US20240025922, Example 185)
Affinity DataIC50: 100nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HPK1 expressed in baculovirus infected Sf21 insect cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed