BDBM648787 US20240034729, Compound 179

SMILES COC(=O)N1CCO[C@@H](Cc2c(-c3c(F)cc(S(N)(=O)=O)cc3Cl)nc3cc(Cl)ccn23)C1

InChI Key InChIKey=JLEIKHGGNBVZTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648787   

TargetP2X purinoceptor 3(Human)
Wuhan Ll Science and Technology Development

US Patent
LigandChemical structure of BindingDB Monomer ID 648787BDBM648787(US20240034729, Compound 179)
Affinity DataIC50: 0.400nMAssay Description:The antagonist property of the compounds disclosed herein was determined using the FLIPR (fluorescence imaging plate reader) method, showing that the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent