BDBM649763 8-fluoro-4-hydroxy-3-(2- methoxyethyl)-6-(3-(4- (pyrrolidin-1-yl)phenyl)-1,2,4- thiadiazol-5-yl)-3,4-dihydro- 2H-benzo[e][1,3]oxazin-2-one::US20240043395, Compound 179

SMILES COCCN1C(O)c2cc(cc(F)c2OC1=O)-c1nc(ns1)-c1ccc(cc1)N1CCCC1

InChI Key InChIKey=FTGAKYZOANSYNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649763   

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649763(8-fluoro-4-hydroxy-3-(2- methoxyethyl)-6-(3-(4- (p...)
Affinity DataIC50: 200nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649763(8-fluoro-4-hydroxy-3-(2- methoxyethyl)-6-(3-(4- (p...)
Affinity DataIC50: 800nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent