BDBM651979 US11903936, Compound 25
SMILES C[C@H](NC(=O)c1[nH]cc(c1C)C1(CC1)c1ccc(c(c1)C#N)C(F)(F)F)c1nc[nH]n1
InChI Key
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 651979
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: 140nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: 260nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Dog)
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
The Board of Regents of The University of Texas System
US Patent
The Board of Regents of The University of Texas System
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair