BDBM652439 5-(2-{6-[(1-methylpiperidin-4-yl)methoxy]pyridin-3-yl}ethyl)isoquinolin-1-amine::US20240059691, Example 1019

SMILES CN1CCC(COc2ccc(CCc3cccc4c(N)nccc34)cn2)CC1

InChI Key InChIKey=XKTDDALNYPOARH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652439   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652439BDBM652439(US20240059691, Example 1019 | 5-(2-{6-[(1-methylpi...)
Affinity DataIC50: 6.50E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent