BDBM652599 2-(4-{[(1-aminoisoquinolin-6-yl)amino]methyl}phenyl)-1-(4-methylpiperazin-1- yl)ethanone::US20240059691, Example 2179

SMILES CN1CCN(CC1)C(=O)Cc1ccc(CNc2ccc3c(N)nccc3c2)cc1

InChI Key InChIKey=VMCOQPKFNGBOQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652599   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652599BDBM652599(US20240059691, Example 2179 | 2-(4-{[(1-aminoisoqu...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent