BDBM652602 5-N-({2-fluoro-4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}methyl)isoquinoline-1,5- diamine::US20240059691, Example 2182
SMILES CN1CCN(CCc2ccc(CNc3cccc4c(N)nccc34)c(F)c2)CC1
InChI Key InChIKey=RJGXWYMMSWXDBY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 652602
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair