BDBM652620 1-(4-((4-(((1-aminoisoquinolin-6-yl)amino)methyl)-3-fluorobenzyl)oxy)piperidin-1- yl)ethan-1-one::US20240059691, Example 2200

SMILES CC(=O)N1CCC(CC1)OCc1ccc(CNc2ccc3c(N)nccc3c2)c(F)c1

InChI Key InChIKey=UNMCKAKYUMTHLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652620   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652620BDBM652620(US20240059691, Example 2200 | 1-(4-((4-(((1-aminoi...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent