BDBM652673 6-N-{[3-(pyrrolidin-1-ylmethyl)phenyl]methyl}isoquinoline-1,6-diamine::US20240059691, Example 4287

SMILES Nc1nccc2cc(NCc3cccc(CN4CCCC4)c3)ccc12

InChI Key InChIKey=CILUVFWKTWEZAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652673   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652673BDBM652673(US20240059691, Example 4287 | 6-N-{[3-(pyrrolidin-...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent