BDBM652698 6-N-{[2-({3-methyl-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-7-yl}methoxy)pyridin-4- yl]methyl}isoquinoline-1,6-diamine::US20240059691, Example 4413

SMILES Cc1nnc2CC(COc3cc(CNc4ccc5c(N)nccc5c4)ccn3)CCn12

InChI Key InChIKey=FDSAYBOXNBUDLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652698   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652698BDBM652698(US20240059691, Example 4413 | 6-N-{[2-({3-methyl-5...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent