BDBM653599 US11911372, Example 20::US20240277683, Example 20

SMILES COc1ccc(CC2CCCCC2)cc1-c1cc(NS(=O)(=O)c2c(OC)cccc2OC)on1

InChI Key InChIKey=KZVVDBNAXONNNU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653599   

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 3.79E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 3.79E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 6.02E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetHistone acetyltransferase KAT5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 6.02E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 8.19E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 653599BDBM653599(US11911372, Example 20 | US20240277683, Example 20)
Affinity DataIC50: 8.19E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent