BDBM6561 2-((S)-2,6-dioxopiperidin-3-yl)-4-((6-(2- methylpyridin-4-yl)-1-((R)- tetrahydrofuran-3-yl)-1H-indazol-5- yl)amino)isoindoline-1,3-dione::US20240208937, Compound 44

SMILES Cc1cc(-c2cc3c(cnn3[C@@H]3CCOC3)cc2Nc2cccc3c2C(=O)N([C@H]2CCC(=O)NC2=O)C3=O)ccn1

InChI Key InChIKey=BLCJFMITZKDTAW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6561   

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6561BDBM6561(2-((S)-2,6-dioxopiperidin-3-yl)-4-((6-(2- methylpy...)
Affinity DataEC50:  55nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6561BDBM6561(2-((S)-2,6-dioxopiperidin-3-yl)-4-((6-(2- methylpy...)
Affinity DataEC50:  55nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent