BDBM656711 N-(2,2-Difluoroethyl)-2-((4-(7-(((2S,5R)-5-((1- ethyl-1H-pyrazole)-4-sulfonamido)tetrahydro-2H- pyran-2-yl)methyl)-2,7-diazaspiro[3.5]nonan-2- yl)pyrimidin-5-yl)oxy)-5-fluoro-N- isopropylbenzamide::US11919901, Compound 106

SMILES CCn1cc(cn1)S(=O)(=O)N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)c3ncncc3Oc3ccc(F)cc3C(=O)N(CC(F)F)C(C)C)CC2)OC1

InChI Key InChIKey=FNQJLOBGFLYIEG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656711   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656711BDBM656711(N-(2,2-Difluoroethyl)-2-((4-(7-(((2S,5R)-5-((1- et...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent