BDBM656798 2-((5-(7-(((2R,5S)-5-(N- Ethylsulfamoyl)amino)tetrahydro-2H-pyran-2- yl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)-1,2,4- triazin-6-yl)oxy)-5-fluoro-N-isopropyl-N-(2,2,2- trifluoroethyl)benzamide::US11919901, Compound 193

SMILES CCNS(=O)(=O)N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)c3ncnnc3Oc3ccc(F)cc3C(=O)N(CC(F)(F)F)C(C)C)CC2)OC1

InChI Key InChIKey=CMPCJYHTJFKRHZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656798   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656798BDBM656798(2-((5-(7-(((2R,5S)-5-(N- Ethylsulfamoyl)amino)tetr...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent