BDBM656814 (S)-N-((3R,6S)-6-((2-(5-(2-((3R,5R)-3,5- Dimethylmorpholine-4-carbonyl)-4- fluorophenoxy)pyrimidin-4-yl)-2,7- diazaspiro[3.5]nonan-7-yl)methyl)tetrahydro-2H- pyran-3-yl)-2-methylpyrrolidine-1-sulfonamide::US11919901, Compound 209

SMILES C[C@H]1CCCN1S(=O)(=O)N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)c3ncncc3Oc3ccc(F)cc3C(=O)C3[C@H](C)COC[C@H]3C)CC2)OC1

InChI Key InChIKey=CLABASFHGRGNJH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656814   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656814BDBM656814((S)-N-((3R,6S)-6-((2-(5-(2-((3R,5R)-3,5- Dimethylm...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent