BDBM656836 5-Fluoro-N,N-diisopropyl-2-((4-(7-(((2S,5R)-5-(N'- methylphenylsulfonoamidimidamido)tetrahydro- 2H-pyran-2-yl)methyl)-2,7-diazaspiro[3.5]nonan-2- yl)pyrimidin-5-yl)oxy)benzamide::US11919901, Compound 232

SMILES CN=S(=O)(N[C@@H]1CC[C@@H](CN2CCC3(CN(C3)c3ncncc3Oc3ccc(F)cc3C(=O)N(C(C)C)C(C)C)CC2)OC1)c1ccccc1

InChI Key InChIKey=IEUPXSMOCGCVNL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656836   

TargetHistone-lysine N-methyltransferase 2A/Menin(Human)
Syndax Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 656836BDBM656836(5-Fluoro-N,N-diisopropyl-2-((4-(7-(((2S,5R)-5-(N'-...)
Affinity DataKi: <1nMAssay Description:Table 4: For Ki determination, individual compounds were prepared as 10 mM DMSO stock solutions. Considering DMSO as the vehicle in the assay system....More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent