BDBM657048 2-(3-(5-Amino-6-(1H-pyrazol-4-yl)pyrazin- 2-yl)-4-methylphenyl)-3,3,3- trifluoropropane-1,2-diol, trifluoroacetate salt (single enantiomer isolated, believed to be (S)-2-(3-(5-Amino-6-(1H-pyrazol-4- yl)pyrazin-2-yl)-4-methylphenyl)-3,3,3- trifluoropropane-1,2-diol)::2-(3-(5-Amino-6-(1H-pyrazol-4-yl)pyrazin-2-yl)-4-methylphenyl)-3,3,3-trifluoropropane-1,2-diol::US11926616, Example 3

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)-c1cn[nH]c1)C(O)(CO)C(F)(F)F

InChI Key InChIKey=UAWHPWKJFBCNKU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657048   

LigandPNGBDBM657048(US11926616, Example 3 | 2-(3-(5-Amino-6-(1H-pyrazo...)
Affinity DataIC50: 100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent

LigandPNGBDBM657048(US11926616, Example 3 | 2-(3-(5-Amino-6-(1H-pyrazo...)
Affinity DataIC50: 100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent