BDBM657179 (S)-3-Amino-6-(5-(1,1-difluoro-2,3- dihydroxypropan-2-yl)-2-methylphenyl)-N- isopropylpyrazine-2-carboxamide, trifluoroacetate salt (single enantiomer)::(S)-3-Amino-6-(5-(1,1-difluoro-2,3-dihydroxypropan-2-yl)-2-methylphenyl)-N-isopropylpyrazine-2-carboxamide::US11926616, Example 46

SMILES CC(C)NC(=O)c1nc(cnc1N)-c1cc(ccc1C)[C@](O)(CO)C(F)F

InChI Key InChIKey=INKQOBAWLDRCKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657179   

LigandPNGBDBM657179((S)-3-Amino-6-(5-(1,1-difluoro-2,3-dihydroxypropan...)
Affinity DataIC50: 100nMAssay Description:PI3Kγ (p110γ) Recombinant Human Protein was purchased from Life technology (Grand Island, NY). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent

LigandPNGBDBM657179((S)-3-Amino-6-(5-(1,1-difluoro-2,3-dihydroxypropan...)
Affinity DataIC50: 100nMAssay Description:PI3Kδ (p110δ/p85α) Recombinant Human Protein was purchased from Eurofins (St Charles, MO). ATP, MgCl2, DTT, EDTA, MOPS and CHAPS were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent