BDBM65867 (1-benzyl-4-piperidyl)-(4-chlorobenzyl)amine::1-benzyl-N-(4-chlorobenzyl)-4-piperidinamine::1-benzyl-N-[(4-chlorophenyl)methyl]piperidin-4-amine::MLS000974662::N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-piperidinamine::N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-amine::SMR000496472::cid_784405

SMILES Clc1ccc(CNC2CCN(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=NQBDQXKOFMTXFA-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 65867   

TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65867BDBM65867(N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-pipe...)
Affinity DataIC50: 660nMAssay Description:Inhibition of human BACE1 using as 7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid beta/A4 precursor protein 770 fragment 667-676-(2,4-dinitrophe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65867BDBM65867(N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-pipe...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine iodide as substrate pre-incubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 65867BDBM65867(N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-pipe...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human serum butyrylcholinesterase using BTCI as substrate pre-incubated for 10 mins followed by substrate addition and measured for 6 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetInward rectifier potassium channel 2(Mouse)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 65867BDBM65867(N-[(4-chlorophenyl)methyl]-1-(phenylmethyl)-4-pipe...)
Affinity DataIC50: 3.77E+4nMAssay Description:Data Source: Johns Hopkins Ion Channel Center (JHICC) BioAssay Type: Confirmatory, Confirmatory Screening, Multiple Concentration Activity Observed. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay