BDBM659937 3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-5-yl)-3-oxoprop-1-en-1-yl N-cyclopropyl-7-hydroxy-4-((1-methylcyclopropyl)methyl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 374

SMILES CC1(Cn2c3c(\C=C\C(=O)N4C[C@H]5C[C@@H]4CO5)cnn3c(O)c(C(=O)NC3CC3)c2=O)CC1

InChI Key InChIKey=YVHXJPXESFREEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659937   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659937(3-((E)-3-((1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-...)
Affinity DataIC50: 0.650nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent