BDBM659995 N-Cyclopropyl-3-((E)-3-((3S,5S)-3,5-dimethylmorpholino)-3-oxoprop-1-en-1-yl)-7-hydroxy-4-isobutyl-2-(methylamino)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 432

SMILES CNc1nn2c(O)c(C(=O)NC3CC3)c(=O)n(CC(C)C)c2c1\C=C\C(=O)N1[C@@H](C)COC[C@@H]1C

InChI Key InChIKey=XQZWYSQKQPRWCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659995   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659995(N-Cyclopropyl-3-((E)-3-((3S,5S)-3,5-dimethylmorpho...)
Affinity DataIC50: 0.660nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent