BDBM661533 US20240101572, Example 142

SMILES CC(=O)Nc1cccc2[nH]c(C(=O)N[C@@H](C)C[C@H]3CC[C@]4(CC3)OC(=O)NN=C4c3ccc(F)cc3)cc12

InChI Key InChIKey=FUIRMTPYCLQWFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661533   

TargetPhospholipase D2(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 661533BDBM661533(US20240101572, Example 142)
Affinity DataIC50: 10nMAssay Description:A DMSO or test substance solution (the DMSO final concentration: 5%) prepared by diluting DMSO or test substance with an Assay buffer (50 mmol/L HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

TargetPhospholipase D1(Human)
Japan Tobacco

US Patent
LigandChemical structure of BindingDB Monomer ID 661533BDBM661533(US20240101572, Example 142)
Affinity DataIC50: 22nMAssay Description:A DMSO or test substance solution (the DMSO final concentration: 5%) prepared by diluting DMSO or test substance with an Assay buffer (50 mmol/L HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent