BDBM663735 US20240109912, Compound 60::US20240109912, Compound 83

SMILES C[C@H]1Oc2cnc(cc2Nc2ncnc(N3CCOCC3)c12)C1CCN(CC1)C1CN(C1)C(=O)C=C

InChI Key InChIKey=QOWNOTMWUWWPAP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 663735   

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663735(US20240109912, Compound 60 | US20240109912, Compou...)
Affinity DataKi:  0.0590nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetCyclin-dependent kinase 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM663735(US20240109912, Compound 60 | US20240109912, Compou...)
Affinity DataKi:  0.283nMAssay Description:CDK7 activity is measured by following the production of ADP generated from ATP-dependent phosphorylation of the peptide substrate derived from RNA P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent