BDBM666449 US20240116946, Example 482

SMILES COc1cc(-c2cc3[nH]c(=O)n(-c4cncc5ccsc45)c(=O)c3s2)c(Cl)cc1F

InChI Key InChIKey=AKDIBZGGWVTDKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 666449   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666449(US20240116946, Example 482)
Affinity DataIC50: 2.54nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent