BDBM668365 US20240124469, Compound TP-3654

SMILES CC(C)(O)C1CCC(Nc2ccc3ncc(-c4cccc(C(F)(F)F)c4)n3n2)CC1

InChI Key InChIKey=XRNVABDYQLHODA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 668365   

TargetSerine/threonine-protein kinase pim-1(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 668365BDBM668365(US20240124469, Compound TP-3654)
Affinity DataIC50: 55nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-3(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 668365BDBM668365(US20240124469, Compound TP-3654)
Affinity DataIC50: 550nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Hangzhou Biosun Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 668365BDBM668365(US20240124469, Compound TP-3654)
Affinity DataIC50: 550nMAssay Description:PIM1, PIM2, and PIM3 (all three kinases are from Carna) were each prepared with 1× Kinase buffer into a kinase solution at a concentration that was 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent