BDBM668477 US20240124487, Compound 17::US20240124487, Compound 18

SMILES CC1OCc2cc(CCc3cc(OCCCn4c(C(O)=O)c(C)c5c(-c6c(C)n(C)nc16)c(Cl)ccc45)c1ccc(F)cc1c3)n(C)n2

InChI Key InChIKey=SWWJSUVLMMBHEP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 668477   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668477(US20240124487, Compound 17 | US20240124487, Compou...)
Affinity DataKi:  0.0100nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM668477(US20240124487, Compound 17 | US20240124487, Compou...)
Affinity DataKi:  0.0420nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent