BDBM668506 US11963960, Example 163

SMILES CN1CCN(CC1)[C@H]1CC[C@@H](CC1)c1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnn12

InChI Key InChIKey=DGCXIZXPTXYQSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 668506   

TargetTyrosine-protein kinase HCK(Human)
Flash Therapeutics

US Patent
LigandPNGBDBM668506(US11963960, Example 163)
Affinity DataIC50: 1.10nMAssay Description:HCK kinase reaction (10 μL) containing 4 nM N-terminally GST-tagged HCK (75-526), purified from insect expression system, 5 μM Control AMC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2024
Entry Details
US Patent