BDBM669522 3-chloro-N-(2-(2,6-dioxopiperidin-3- yl)-1,3-dioxoisoindolin-5-yl)-4- methylbenzenesulfonamide::US20240132463, Compound 7

SMILES Cc1ccc(cc1Cl)S(=O)(=O)Nc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=WVKNOEMSHFZOMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669522   

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669522(US20240132463, Compound 7 | 3-chloro-N-(2-(2,6-dio...)
Affinity DataIC50: 13nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent