BDBM669904 Production of 3-(5-acetylthiophen-2-yl)-3-[3-({4-[2-(benzyloxy)ethyl]-1,1-dioxide-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl}methyl)-4-methylphenyl]-2-methylpropanoic acid ::US20240132519, Compound 13

SMILES CC(C(c1ccc(s1)C(C)=O)c1ccc(C)c(CN2CC(CCOc3ccccc3)Oc3ccccc3S2(=O)=O)c1)C(O)=O

InChI Key InChIKey=SDBGKLJKVGXOQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 669904   

LigandPNGBDBM669904(US20240132519, Compound 13 | Production of 3-(5-ac...)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of each compound on the binding between NRF2 and KEAP1 was measured by bioluminescence resonance energy transfer (BRET) assay...More data for this Ligand-Target Pair
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Date in BDB:
7/16/2024
Entry Details
US Patent