BDBM670906 3-(3-(difluoromethoxy)phenyl)-1-(5- fluoropyridin-2-yl)-N-(3-methyl-1,1- dioxidothietan-3-yl)-1,5,6,7- tetrahydropyrano[3,2-c]pyrazole-6- carboxamide (mixture of enantiomers)::US20240140938, Example 119

SMILES CC1(CS(=O)(=O)C1)NC(=O)C1COc2c(C1)n(nc2-c1cccc(OC(F)F)c1)-c1ccc(F)cn1

InChI Key InChIKey=VSZFMKKMVDIOCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670906   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM670906(US20240140938, Example 119 | 3-(3-(difluoromethoxy...)
Affinity DataIC50: 0.330nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13C18-triolein (13C-1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent