BDBM67137 3-[[4-(1-adamantyl)-1,3-thiazol-2-yl]methyl]-2-[(4-methylpiperazin-1-yl)methylidene]-1H-quinazolin-4-one::3-[[4-(1-adamantyl)-2-thiazolyl]methyl]-2-[(4-methyl-1-piperazinyl)methylidene]-1H-quinazolin-4-one::3-[[4-(1-adamantyl)thiazol-2-yl]methyl]-2-[(4-methylpiperazino)methylene]-1H-quinazolin-4-one::SR-03000001029-1::cid_44202995

SMILES CO[C@H]1CCN(C2CC3(CCOCC3)c3ccc(Nc4ccc(-c5cnc6cc(F)ccn56)c5c4C(=O)NC5)nc32)C1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 67137   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67137BDBM67137(US20250361241, Compound 76)
Affinity DataIC50: 3.55nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67137BDBM67137(US20250361241, Compound 76)
Affinity DataIC50: 286nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent