BDBM673751 (1r,4S,4′R,8′S)-4-(3-chloroanilino)-4′-methyl-8′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-3′,4′,8′,9′-tetrahydro-2′H-spiro[cyclohexane-1,7′-indeno[5,6-b][1,4]dioxepine]-4-carboxylic acid::US20240150293, Example 987

SMILES C[C@@H](COc1ccnc2CCC[C@@H](C)c12)C[C@H]1Cc2cc3OCC[C@@H](C)Oc3cc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=FKVAEWJLDPGUBO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673751   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673751(US20240150293, Example 987 | (1r,4S,4′R,8...)
Affinity DataKi:  0.00400nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent