BDBM674652 US20240158357, Example 12

SMILES CC(=O)Nc1ccc(cc1)-c1nc2ccsc2c(=O)n1-c1cccnc1

InChI Key InChIKey=SHSMDFCGMHXOFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 674652   

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM674652(US20240158357, Example 12)
Affinity DataIC50: 3.72E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM674652(US20240158357, Example 12)
Affinity DataIC50: 7.60E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent