BDBM674677 US20240158368, Compound 24

SMILES N#Cc1cc(C(=O)N2CCN(CC3CCCO3)CC2)c(N2CC[C@@H](NC(=O)c3cc(=O)[nH]c4c(F)cccc34)C2)c(C(F)(F)F)c1

InChI Key InChIKey=FZNOFHXFLLRLLL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 674677   

TargetReplicase polyprotein 1ab(2019-nCoV)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 674677BDBM674677(US20240158368, Compound 24)
Affinity DataEC50:  0.520nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-OC43)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 674677BDBM674677(US20240158368, Compound 24)
Affinity DataEC50:  0.740nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 674677BDBM674677(US20240158368, Compound 24)
Affinity DataEC50:  1.56nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent