BDBM6754 1,7-Annulated indolocarbazole deriv. 13Bg::24-(hydroxymethyl)-9-methyl-1,9,14-triazaheptacyclo[16.7.1.0^{2,17}.0^{3,11}.0^{6,10}.0^{12,16}.0^{22,26}]hexacosa-2(17),3(11),4,6(10),7,12(16),18(26),19,21-nonaene-13,15-dione

SMILES Cn1ccc2ccc3c4n5CC(CO)Cc6cccc(c4c4C(=O)NC(=O)c4c3c12)c56

InChI Key InChIKey=FMZCXIHHKPGEAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6754   

LigandPNGBDBM6754(24-(hydroxymethyl)-9-methyl-1,9,14-triazaheptacycl...)
Affinity DataIC50: 84nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6754(24-(hydroxymethyl)-9-methyl-1,9,14-triazaheptacycl...)
Affinity DataIC50: 650nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed