BDBM67552 1-[7-difluoro- methyl-6-(1- methyl-1H- pyrazol-4-yl)- 3,4-dihydro-2H- quinolin-1-yl]- isoquinoline- 3-carboxylic acid amide::US12486251, Example 3

SMILES Cn5cc(c4cc3CCCN(c1nc(C(N)=O)cc2ccccc12)c3cc4C(F)F)cn5

InChI Key InChIKey=ULMIPFIFTWOJIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67552   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 67552BDBM67552(1-[7-difluoro- methyl-6-(1- methyl-1H- pyrazol-4-y...)
Affinity DataIC50: 245nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent