BDBM67557 US12486251, Example 8::{1-[7-difluoro- methyl-6-(1- methyl-1H- pyrazol-4-yl)- 3,4-dihydro-2H- quinolin-1-yl]- isoquinolin-3- yl}-(3-hydroxy- azetidine- 1-yl)methanone

SMILES Cn6cc(c5cc4CCCN(c2nc(C(=O)N1CC(O)C1)cc3ccccc23)c4cc5C(F)F)cn6

InChI Key InChIKey=PQDUQOFWXAYHCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67557   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 67557BDBM67557({1-[7-difluoro- methyl-6-(1- methyl-1H- pyrazol-4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent