BDBM676510 US20240166642, Example 4a

SMILES O=c1[nH]c(=S)n(Cc2ccc(Cl)cc2[C@H]2COCCN2)c2cc[nH]c12

InChI Key InChIKey=NNRYKNVTEOHNOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 676510   

TargetMyeloperoxidase(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 676510BDBM676510(US20240166642, Example 4a)
Affinity DataIC50: 18.7nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetThyroid peroxidase(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 676510BDBM676510(US20240166642, Example 4a)
Affinity DataIC50: 370nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent