BDBM677633 US20240174662, Example 297

SMILES CN\C(=C(\OC[C@H]1CCN1C[C@H](C)O)C=N)c1ccn2nc(Nc3cnc(C)c(C)n3)cc2c1

InChI Key InChIKey=GEXCHQRXCKBBTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 677633   

TargetSerine/threonine-protein kinase SIK2(Human)
Janssen Biotech

US Patent
LigandPNGBDBM677633(US20240174662, Example 297)
Affinity DataIC50: 0.847nMAssay Description:All steps were performed at room temperature. Compounds were pre-plated onto an assay plate using an Echo acoustic dispenser (Labcyte, E550 or E555) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent