BDBM678408 4-(2-benzyl-2,8-diazaspiro[4.5]decan-8-yl)-2-(pyridin-4-yl)pyrido[3,4-d]pyrimidine ::US20240174696, Compound 133

SMILES C(N1CCC2(C1)CCN(CC2)c1nc(nc2cnccc12)-c1ccncc1)c1ccccc1

InChI Key InChIKey=IOLLREJSIOGZLK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678408   

TargetSerine/threonine-protein kinase LATS2(Human)
Genentech

US Patent
LigandPNGBDBM678408(US20240174696, Compound 133 | 4-(2-benzyl-2,8-diaz...)
Affinity DataKi:  0.0690nMAssay Description:Human LATS2 catalytic domain which contains the amino acids G553-V1088 (accession NP_055387) was purified in-house. The LATS2 catalytic domain was co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent