BDBM679442 6-((4-(1,1-dioxido-4- oxo-1,2,5- thiadiazolidin-2-yl)-3- fluoro-5- hydroxybenzyl) amino)picolinonitrile::US20240180886, Example 40

SMILES Oc1cc(CNc2cccc(n2)C#N)cc(F)c1N1CC(=O)NS1(=O)=O

InChI Key InChIKey=HGRULBLWUSQRBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 679442   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679442(US20240180886, Example 40 | 6-((4-(1,1-dioxido-4- ...)
Affinity DataIC50: 5nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM679442(US20240180886, Example 40 | 6-((4-(1,1-dioxido-4- ...)
Affinity DataIC50: 1.25E+3nMAssay Description:The PTPN2 biochemical assay was performed as follows, a 5× stock solution of human PTPN2 (SRP5075, MilliporeSigma, Burlington, MA) and a 1.25× stock ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent