BDBM680689 5-{6-[2-(4-Chloro-2-cyano-6,7-difluoro-indol-1-yl)-ethylamino]-pyrimidin-4-yl}-3- fluoro-thiophene-2-carboxylic acid::US12011444, Example 904

SMILES OC(=O)c1sc(cc1F)-c1cc(NCCn2c(cc3c(Cl)cc(F)c(F)c23)C#N)ncn1

InChI Key InChIKey=ONNMXZZRWVMENB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680689   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680689(US12011444, Example 904 | 5-{6-[2-(4-Chloro-2-cyan...)
Affinity DataIC50: 1nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680689(US12011444, Example 904 | 5-{6-[2-(4-Chloro-2-cyan...)
Affinity DataIC50: 49nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent