BDBM680987 US12012467, Compound DI-427biotin::US12012467, Compound DI-427biotin-(NC)

SMILES CCC(=O)N[C@@H](Cc1nc2ccc(Cl)cc2s1)C(=O)N[C@@H](C[C@H]1CC[C@H](CNC(=O)COCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@@H]32)CC1)C(=O)N[C@@H](CCCCN(C)C)C(=O)N[C@@H]1CCOc2ccccc21

InChI Key InChIKey=WUCGQHPXNVJVFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680987   

TargetDCN1-like protein 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 680987BDBM680987(US12012467, Compound DI-427biotin | US12012467, Co...)
Affinity DataIC50: 189nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent

TargetDCN1-like protein 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 680987BDBM680987(US12012467, Compound DI-427biotin | US12012467, Co...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
US Patent