BDBM682883 2-(2-chlorophenyl)-7-(5- fluoroisoquinolin-4-yl)-5,7- diazaspiro[3.4]octane-6,8- dione::US20240208970, Compound 88

SMILES Fc1cccc2cnc(Cl)c(N3C(=O)NC4(CC(C4)c4ccccc4Cl)C3=O)c12

InChI Key InChIKey=VPKWOUVEIQMIRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682883   

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682883(US20240208970, Compound 88 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 253nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent