BDBM683080 4-(6-(3-amino-8-a- zabicyclo[3.2.1]oc- tane-8-yl)-3-(5- fluoro-3- methylben- zo[d]isoxazol-6-yl)- 4-hydroxypyridin- 2-yl)-2-fluoroben- zonitrile::US20240216357, Example 24

SMILES Cc1noc2cc(c(F)cc12)-c1c(O)cc(nc1-c1ccc(C#N)c(F)c1)N1C2CCC1CC(N)C2

InChI Key InChIKey=JYIUJQGLHHBGDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683080   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM683080(US20240216357, Example 24 | 4-(6-(3-amino-8-a- zab...)
Affinity DataIC50: 21.5nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
US Patent