BDBM683185 2-fluoro-4-(8- (3-hydroxy-4- methoxyphenyl)- 5-(4- (methylamino) piperidin-1-yl) imidazolo[1,2- c]pyrimidin-7- yl)benzonitrile hydrochloride::US20240216357, Example 138

SMILES CNC1CCN(CC1)c1nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(OC)c(O)c2)c2nccn12

InChI Key InChIKey=OZVLQLOZOJCHMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683185   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683185(US20240216357, Example 138 | 2-fluoro-4-(8- (3-hyd...)
Affinity DataIC50: 0.100nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
US Patent